7-Ketolithocholic acid

7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion[1][2].

Product Specifications

CAS Number

[4651-67-6]

Product Name Alternative

3α-Hydroxy-7-oxo-5β-cholanic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/7-ketolithocholic-acid.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])C(C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O

Molecular Formula

C24H38O4

Molecular Weight

390.56

Precautions

H302, H315, H319, H335

References & Citations

[1]Choucair I, et al. Quantification of bile acids: a mass spectrometry platform for studying gut microbe connectionto metabolic diseases. J Lipid Res. 2020 Feb;61 (2) :159-177.|[2]Salen G, et al. Effect of 7-ketolithocholic acid on bile acid metabolism in humans. Gastroenterology. 1982 Aug;83 (2) :341-7.