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Procyclidine-d5

Procyclidine-d5 (Tricyclamol-d5) is deuterium labeled Procyclidine (hydrochloride) . Procyclidine (Tricyclamol, (±) -Procyclidine) hydrochloride , an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine hydrochloride can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy[1][2][3].

Product Specifications

Product Name Alternative

Tricyclamol-d5; (±) -Procyclidine-d5

UNSPSC

12352005

Target

IGluR; Isotope-Labeled Compounds; mAChR

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

OC(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])(C2CCCCC2)CCN3CCCC3

Molecular Formula

C19H24D5NO

Molecular Weight

292.47

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yun-Bae Kim, et al. Effects of combinational prophylactics composed of physostigmine and procyclidine on soman-induced lethality, seizures and brain injuries. Environ Toxicol Pharmacol. 2002 Jan;11 (1) :15-21.|[3]Ulrich Ettinger, et al. Effects of procyclidine on eye movements in schizophrenia. Neuropsychopharmacology. 2003 Dec;28 (12) :2199-208.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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