ω-conotoxin MoVIA
Product Specifications
UNSPSC Description
ω-conotoxin MoVIA is a potent and selective Cav2.2 inhibitor with an IC50 of 0.33 μM in SH-SY5Y fluorimetric hCav2.2 assay[1].
Target Antigen
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(NCC(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@H](NC1=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@H]3CCCNC(N)=N)=O)=O)=O)=O)=O)=O)C(N[C@@H](CO)C(N4C[C@H](O)C[C@H]4C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@H](NC3=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CSSC[C@@H]7N)C(N[C@@H]([C@H](O)C)C(N[C@H]1[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H]8C[C@H](CN8C([C@H]9N(C([C@H](CCCCN)NC7=O)=O)CCC9)=O)O
Molecular Weight
3607.15
References & Citations
[1]Sousa SR, et al. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Sci Rep. 2018 Sep 7;8(1):13397.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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