Lyso-PAF C-18

Lyso-PAF C-18 is an intermediate for the synthesis of C18-PAF (HY-130345) . It has an easily substituted "Lyso-PAF" structure and is easy to purify and has high yield. C18-PAF is a ligand for platelet-activating factor and PAF G protein-coupled receptor (PAFR) and has renovasodilator properties and antihypertensive lipid properties[1][2].

Product Specifications

CAS Number

[74430-89-0]

UNSPSC

12352211

Target

Endogenous Metabolite; Platelet-activating Factor Receptor (PAFR)

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/lyso-paf-c-18.html

Purity

99.7

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCCOC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O

Molecular Formula

C26H56NO6P

Molecular Weight

509.70

References & Citations

[1]Heymans F, et al. New total synthesis and high resolution 1H NMR spectrum of platelet-activating factor, its enantiomer and racemic mixtures[J]. Biochimica et Biophysica Acta (BBA) -Lipids and Lipid Metabolism, 1981, 666 (2) : 230-237.|[2]Vargaftig BB, et al. Background and present status of research on platelet-activating factor (PAF-acether) . Ann N Y Acad Sci. 1981;370:119-37.