HPK1 ligand 2
HPK1 ligand 2 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). HPK1 ligand 2 can be used for synthesis DD205-291.
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-ligand-2.html
Smiles
FC(F)(F)CN(N=C1)C=C1C2=CNC(N=C3)=C2N=C3C4=CC=C(Br)N=C4
Molecular Formula
C16H10BrF3N6
Molecular Weight
423.19
References & Citations
[1]Zhimin Zhang, et al. Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy. J Med Chem. 2024 Nov 14;67 (21) :18682-18698.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog