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HPK1 ligand 2

HPK1 ligand 2 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). HPK1 ligand 2 can be used for synthesis DD205-291.

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hpk1-ligand-2.html

Smiles

FC(F)(F)CN(N=C1)C=C1C2=CNC(N=C3)=C2N=C3C4=CC=C(Br)N=C4

Molecular Formula

C16H10BrF3N6

Molecular Weight

423.19

References & Citations

[1]Zhimin Zhang, et al. Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy. J Med Chem. 2024 Nov 14;67 (21) :18682-18698.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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