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Bestatin-amide-PEG3-CH2-acid

Bestatin-amide-PEG3-CH2-acid is an E3 ligase ligand-linker conjugate. Bestatin-amide-PEG3-CH2-acid can be used to synthesize PROTAC RAR Degrader-1 (HY-111844) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bestatin-amide-peg3-ch2-acid.html

Smiles

O=C([C@@H](O)[C@H](N)CC1=CC=CC=C1)N[C@@H](CC(C)C)C(NCCOCCOCCOCC(O)=O)=O

Molecular Formula

C24H39N3O8

Molecular Weight

497.58

References & Citations

[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19 (22) :6768-78.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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