H-151
H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease[1].
Product Specifications
CAS Number
941987-60-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/h-151.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CNC2=C1C=CC=C2)NC3=CC=C(CC)C=C3
Molecular Formula
C17H17N3O
Molecular Weight
279.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Haag SM, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559 (7713) :269-273.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Clostridium Kluyveri rplL Protein (aa 1-123) (strain NBRC 12016)
![P23 (PTGES3) Mouse Monoclonal Antibody [Clone 1H5]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)