Anti-Hu SIGLEC8 PE

*Galeotti C, Stephen-Victor E, Karnam A, Das M, Gilardin L, Maddur MS, Wymann S, Vonarburg C, Chevailler A, Dimitrov JD, Benveniste O, Bruhns P, Kaveri SV, Bayry J: Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE. J Allergy Clin Immunol. 2019 Aug;144 (2) :524-535.e8., URL: https://www.ncbi.nlm.nih.gov/pubmed/30529242, *Kano G, Bochner BS, Zimmermann N: Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases. Immunobiology. 2017 Feb;222 (2) :343-349., URL: https://www.ncbi.nlm.nih.gov/pubmed/27682013, *Arakawa S, Suzukawa M, Ohshima N, Tashimo H, Asari I, Matsui H, Kobayashi N, Shoji S, Nagase T, Ohta K: Expression of Siglec-8 is regulated by interleukin-5, and serum levels of soluble Siglec-8 may predict responsiveness of severe eosinophilic asthma to mepolizumab. Allergol Int. 2018 Sep;67S:S41-S44., URL: https://www.ncbi.nlm.nih.gov/pubmed/29703694, *Kano G, Almanan M, Bochner BS, Zimmermann N: Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation. J Allergy Clin Immunol. 2013 Aug;132 (2) :437-45., URL: https://pubmed.ncbi.nlm.nih.gov/23684072/