EC119
EC119 consists of Pteroic acid-gGlu-Asp-Arg-Asp-Asp-Cys, which is the folate–peptide moiety found within both the EC140 and EC145 structures[1].
Product Specifications
CAS Number
[742091-99-2]
UNSPSC
12352209
Target
Folate Receptor (FR)
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ec119.html
Smiles
O=C1C2=NC(CNC(C=C3)=CC=C3C(N[C@H](C(O)=O)CCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=CNC2=NC(N)=N1
Molecular Formula
C40H51N15O17S
Molecular Weight
1045.99
References & Citations
[1]Christopher P Leamon, et al. Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145. Int J Cancer. 2007 Oct 1;121 (7) :1585-92.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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