Tubulin polymerization-IN-63
Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC50 value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research[1].
Product Specifications
CAS Number
3040385-73-4
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-63.html
Smiles
Cl[Cu]12([N]3(C4)CCOCC3)[N](N=C(NC5=CC(C)=C(O)C(C)=C5)S2)=CC6=CC=CC4=[N]61
Molecular Formula
C20H24ClCuN5O2S
Molecular Weight
497.50
References & Citations
[1]Milunovic MNM, et al. Copper (II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubulin Polymerization: The Morpholine Position Matters. J Med Chem. 2024 Jun 13;67 (11) :9069-9090.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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