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PEN (rat) (TFA)

PEN (rat) TFA, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83[1].

Product Specifications

UNSPSC

12352209

Target

G protein-coupled Bile Acid Receptor 1

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pen-rat-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](N)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N1[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CCCNC(N)=N)=O)CC(C)C)=O)CC(C)C)=O)C)=O)=O)CC(C)C)=O)C(C)C)=O)CC(N)=O)=O)CCC(O)=O)=O)CCC3)=O)CCC2)=O)C(C)C)=O)CCC(O)=O)=O)CCC1)=O)=O)CC(C)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(O)=O)=O)C(C)C.OC(C(F)(F)F)=O.[x]

Molecular Formula

C102H169N27O33.xC2HF3O2

Molecular Weight

2301.59 (free base)

References & Citations

[1]Seshat M Mack, et al. Neuropeptide PEN and Its Receptor GPR83: Distribution, Signaling, and Regulation. ACS Chem Neurosci. 2019 Apr 17;10 (4) :1884-1891.|[2]Ivone Gomes, et al. Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci Signal. 2016 Apr 26;9 (425) :ra43.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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