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Ketoprofen (lysinate) (Standard)

Ketoprofen (lysinate) (Standard) is the analytical standard of Ketoprofen (lysinate) . This product is intended for research and analytical applications. Ketoprofen (RP-19583) lysinate is a non-steroidal anti-inflammatory agent. Ketoprofen lysinate can inhibit the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2) . which is potential in the research of inflammation, immunology, and metabolic disease such as obesity[1][2][3].

Product Specifications

CAS Number

57469-78-0

Product Name Alternative

RP-19583 (lysinate) (Standard)

UNSPSC

12352005

Target

COX; Reference Standards

Type

Reference compound

Related Pathways

Immunology/Inflammation; Others

Field of Research

Metabolic Disease; Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/ketoprofen-lysinate-standard.html

Smiles

N[C@@H](CCCCN)C(O)=O.O=C(O)C(C)C1=CC=CC(C(C2=CC=CC=C2)=O)=C1

Molecular Formula

C22H28N2O5

Molecular Weight

400.47

References & Citations

[1]Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12 (4) :533-7.|[2]NamHyeon Kang Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway. Pflugers Arch. 2020 May;472 (5) :583-596. |[3]Denisa Dan, et al. Ketoprofen affects the mammary immune response in dairy cows in vivo and in vitro. J Dairy Sci. 2018 Dec;101 (12) :11321-11329.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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