What is the catalog number for SpHistin?

The catalog number for SpHistin is HY-P5680.

What sizes are available for SpHistin?

SpHistin is available in the following size(s): 1 Each.

Is SpHistin in stock?

SpHistin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SpHistin?

SpHistin is manufactured by QuantiMol.

What is the estimated delivery time for SpHistin?

Estimated delivery time for SpHistin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SpHistin?

The safety data sheet for SpHistin is available here: http://file.medchemexpress.com/batch_PDF/HY-P5680/.

SpHistin

SpHistin is an antimicrobial peptide (AMP). SpHistin can bind to LPS and permeabilize the bacterial membrane. SpHistin combined with Rifampicin (HY-B0272) and Azithromycin (HY-17506) promotes the intracellular uptake of the antibiotics and subsequently enhances the bactericidal activity of both agents against P. aeruginosa[1].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sphistin.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](C)C(NCC(NCC(N[C@@H](CCCCN)C(N[C@@H](C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(NCC(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N

Molecular Formula

C170H293N61O45S

Molecular Weight

3943.59

References & Citations

[1]Jie Liu, et al. The Synergistic Effect of Mud Crab Antimicrobial Peptides Sphistin and Sph12-38 With Antibiotics Azithromycin and Rifampicin Enhances Bactericidal Activity Against Pseudomonas Aeruginosa. Front Cell Infect Microbiol. 2020 Oct 23:10:572849.