Caerin 1.1 (TFA)
Caerin 1.1 TFA is a host defense peptide isolated from the glandular secretions of the Australian tree frog Litoria. Caerin 1.1 TFA inhibits HeLa cell proliferation and mediates apoptosis. Caerin 1.1 TFA may enhance adaptive T cell immune responses[1].
Product Specifications
UNSPSC
12352209
Target
Apoptosis
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caerin-1-1-tfa.html
Purity
98.14
Solubility
10 mM in DMSO
Smiles
NCC(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CN=CN1)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N)=O)CC(C)C)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C121H203N33O29.xC2HF3O2
Molecular Weight
2584.11 (free base)
References & Citations
[1]Ni G, et al. Host-Defense Peptides Caerin 1.1 and 1.9 Stimulate TNF-Alpha-Dependent Apoptotic Signals in Human Cervical Cancer HeLa Cells. Front Cell Dev Biol. 2020 Jul 31;8:676.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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