BRD9 Degrader-4
BRD9 Degrader-4 (BRD9c), a bifunctional molecular glue, is a potent BRD9 degrader with a DC50 of ≤25 nM. BRD9 Degrader-4 has anti-cancer effects[1].
Product Specifications
CAS Number
[3024541-39-4]
UNSPSC
12352005
Target
Epigenetic Reader Domain; Molecular Glues
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd9-degrader-4.html
Smiles
CC(C(C1=CC(OC)=C(C(OC)=C1)CN2CCN(CCC2)C(/C(C#N)=C/C(C)(C)C)=O)=CN3C)=C(C)C3=O
Molecular Formula
C30H40N4O4
Molecular Weight
520.66
References & Citations
[1]Andrea TESTA, et al. Bifunctional molecules for targeted protein degradation. WO2023242597A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD9
Curated Selection
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