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Nitrofurazone (Standard)

Nitrofurazone (Standard) is the analytical standard of Nitrofurazone. This product is intended for research and analytical applications. Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria[1][2][3][4][5].

Product Specifications

CAS Number

59-87-0

Product Name Alternative

Nitrofural (Standard)

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nitrofurazone-standard.html

Smiles

O=C(N/N=C/C1=CC=C([N+]([O-])=O)O1)N

Molecular Formula

C6H6N4O4

Molecular Weight

198.14

References & Citations

[1]Ryan A, et al. Activation of nitrofurazone by azoreductases: multiple activities in one enzyme. Sci Rep. 2011;1:63.|[2]McCalla DR, et al. Mode of action of nitrofurazone. J Bacteriol. 1970 Dec;104 (3) :1126-34.|[3]Tu Y, et al. Effect of nitrofurazone on bacterial RNA and ribosome synthesis and on the function of ribosomes. Chem Biol Interact. 1976 Jul;14 (1-2) :81-91.|[4]Z Kari FW, et al. Toxicity and carcinogenicity of nitrofurazone in F344/N rats and B6C3F1 mice. Food Chem Toxicol. 1989 Feb;27 (2) :129-37.|[5]Neal RA, et al. The activity of nitrofurazone and furazolidone against Leishmania donovani, L. major and L. enriettii in vitro and in vivo. Ann Trop Med Parasitol. 1988 Oct;82 (5) :453-6.|[6]Takahashi M, et al. Possible mechanisms underlying mammary carcinogenesis in female Wistar rats by nitrofurazone. Cancer Lett. 2000 Aug 11;156 (2) :177-84.|[7]Hiraku Y, et al. Mechanism of carcinogenesis induced by a veterinary antimicrobial drug, nitrofurazone, via oxidative DNA damage and cell proliferation. Cancer Lett. 2004 Nov 25;215 (2) :141-50.|[8]Nogueira Filho MA, et al. Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits. Drug Metab Lett. 2013 Mar;7 (1) :58-64.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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