Bradykinin potentiator B

Bradykinin potentiator B (Bradykinin potentiating peptide B) is venom of Agkistrodon halys blomhoffi. Bradykinin potentiator B is a potent ACE inhibitor. Bradykinin potentiator inhibits the activity of bradykinin inhibitory peptidase[1].

Product Specifications

CAS Number

[30892-86-5]

Product Name Alternative

Bradykinin potentiating peptide B

UNSPSC

12352209

Target

Angiotensin-converting Enzyme (ACE)

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bradykinin-potentiator-b.html

Purity

99.94

Solubility

H2O : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N1[C@@H](CCC1)C(O)=O)[C@H]2N(CCC2)C([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H]3N(CCC3)C([C@H](CCCNC(N)=N)NC([C@H]4N(CCC4)C([C@H]5N(CCC5)C([C@H](CC(C)C)NC(CNC([C@@H]6CCC(N6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C56H91N15O13

Molecular Weight

1182.41

References & Citations

[1]Kato H, et, al. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10 (6) :972-80. |[2]Tom B, et, al. Bradykinin potentiation by ACE inhibitors: a matter of metabolism. Br J Pharmacol. 2002 Sep;137 (2) :276-84.