NVS-BPTF-1
NVS-BPTF-1, a chemical probe, is a selective inhibitor for bromodomain and PHD finger containing transcription factor (BPTF), with KD of 71 nM[1].
Product Specifications
CAS Number
2662454-54-6
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nvs-bptf-1.html
Purity
99.6
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC(F)=C(NC2=C(C)C(N(C=C(C3=CN(C4CC4)N=C3)C=C5)C5=N2)=O)C=C1)(N6CCN(C)CC6)=O
Molecular Formula
C26H28FN7O3S
Molecular Weight
537.61
References & Citations
[1]Mélin L, et al., Synthesis of NVS-BPTF-1 and evaluation of its biological activity. Bioorg Med Chem Lett. 2021 Sep 1;47:128208.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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