3-Hydroxykynurenine (Standard)
Product Specifications
UNSPSC Description
3-Hydroxykynurenine (Standard) is the analytical standard of 3-Hydroxykynurenine. This product is intended for research and analytical applications. 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis[1].
Target Antigen
Apoptosis; Endogenous Metabolite
Type
Reference Standards
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-hydroxykynurenine-standard.html
Purity
99.34
Smiles
O=C(O)C(N)CC(C1=CC=CC(O)=C1N)=O
Molecular Weight
224.21
References & Citations
[1]S Okuda, et al. 3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity. J Neurochem. 1998 Jan;70(1):299-307.|[2]Sarah S Zaher,et al. 3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci. 2011 Apr 22;52(5):2640-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113294R/3-Hydroxykynurenine-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113294R/
Clinical Information
No Development Reported
CAS Number
484-78-6
Available Sizes
Curated Selection
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