Oleyl anilide

Oleyl anilide (Oleic acid anilide) is a toxic agent found in some stocks of toxic oil, which is associated with toxic oil syndrome (TOS) . Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT) (IC50: 26 µM) [1][2].

Product Specifications

CAS Number

[5429-85-6]

Product Name Alternative

Oleic acid anilide; OAA

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/oleyl-anilide.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCC/C=C\CCCCCCCC(NC1=CC=CC=C1)=O

Molecular Formula

C24H39NO

Molecular Weight

357.57

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Roth BD, et al. Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents. J Med Chem. 1992 May 1;35 (9) :1609-17.|[2]Cai P, et al. Immunotoxic response of oleic acid anilide and its hydrolysis products in female MRL (+/+) mice. J Immunotoxicol. 2005 Oct 1;2 (4) :231-6.