SM-32504

SM-32504 is an effective ACAT inhibitor that can significantly reduce serum cholesterol levels in mouse models fed with high-fat and high-cholesterol diets. SM-32504 can be used for research on hypercholesterolemia and atherosclerosis[1].

Product Specifications

CAS Number

[185539-34-8]

UNSPSC

12352005

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sm-32504.html

Smiles

O=C(NC1=C(C(C)C)C=CC=C1C(C)C)NC2=C(C3=CC(OC)=CC=C3)C4=C(N=CC=C4)N(CCCC)C2=O

Molecular Formula

C32H38N4O3

Molecular Weight

526.67

References & Citations

[1]Ohnuma S, et al. Synthesis and structure–activity relationship studies on a novel series of naphthylidinoylureas as inhibitors of acyl-CoA: cholesterol O-acyltransferase (ACAT) [J]. Bioorganic & medicinal chemistry letters, 2004, 14 (5) : 1309-1311.