SM-32504
SM-32504 is an effective ACAT inhibitor that can significantly reduce serum cholesterol levels in mouse models fed with high-fat and high-cholesterol diets. SM-32504 can be used for research on hypercholesterolemia and atherosclerosis[1].
Product Specifications
CAS Number
185539-34-8
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sm-32504.html
Smiles
O=C(NC1=C(C(C)C)C=CC=C1C(C)C)NC2=C(C3=CC(OC)=CC=C3)C4=C(N=CC=C4)N(CCCC)C2=O
Molecular Formula
C32H38N4O3
Molecular Weight
526.67
References & Citations
[1]Ohnuma S, et al. Synthesis and structure–activity relationship studies on a novel series of naphthylidinoylureas as inhibitors of acyl-CoA: cholesterol O-acyltransferase (ACAT) [J]. Bioorganic & medicinal chemistry letters, 2004, 14 (5) : 1309-1311.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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