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Sonepiprazole (mesylate)

Sonepiprazole mesylate is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively[1].

Product Specifications

CAS Number

170858-34-1

Product Name Alternative

PNU-101387G (mesylate) ; U-101387G (mesylate)

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sonepiprazole-mesylate.html

Smiles

O=S(C1=CC=C(C=C1)N2CCN(CC2)CC[C@@H]3OCCC4=C3C=CC=C4)(N)=O.CS(=O)(O)=O

Molecular Formula

C22H31N3O6S2

Molecular Weight

497.63

References & Citations

[1]Mark H Corrigan, et al. Effectiveness of the selective D4 antagonist sonepiprazole in schizophrenia: a placebo-controlled trial. Biol Psychiatry. 2004 Mar 1;55 (5) :445-51.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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