Sonepiprazole (mesylate)
Sonepiprazole mesylate is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively[1].
Product Specifications
CAS Number
170858-34-1
Product Name Alternative
PNU-101387G (mesylate) ; U-101387G (mesylate)
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sonepiprazole-mesylate.html
Smiles
O=S(C1=CC=C(C=C1)N2CCN(CC2)CC[C@@H]3OCCC4=C3C=CC=C4)(N)=O.CS(=O)(O)=O
Molecular Formula
C22H31N3O6S2
Molecular Weight
497.63
References & Citations
[1]Mark H Corrigan, et al. Effectiveness of the selective D4 antagonist sonepiprazole in schizophrenia: a placebo-controlled trial. Biol Psychiatry. 2004 Mar 1;55 (5) :445-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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