Lenvatinib N-oxide
Lenvatinib N-Oxide (Lenvatinib impurity 10) is the impurity of Lenvatinib (HY-10981) . Lenvatinib (E7080) is an orally active, multi-targeted tyrosine kinase inhibitor[1].
Product Specifications
CAS Number
[1788901-86-9]
Product Name Alternative
Lenvatinib impurity 10
UNSPSC
12352005
Hazard Statement
H361-H373
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lenvatinib-n-oxide.html
Smiles
O=C(C1=CC2=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C=C[N+]([O-])=C2C=C1OC)N
Molecular Formula
C21H19ClN4O5
Molecular Weight
442.85
Precautions
P260-P280-P405-P501
References & Citations
[1]Kudo M, et al. Lenvatinib versus Bay 43-9006 in first-line treatment of patients with unresectable hepatocellularcarcinoma: a randomised phase 3 non-inferiority trial. Lancet. 2018 Mar 24;391 (10126) :1163-1173.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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