(R) -Zanubrutinib
(R) -Zanubrutinib is the R enantiomer of Zanubrutinib. (R) -Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 11 nM.
Product Specifications
CAS Number
1691249-44-1
Product Name Alternative
(R) -BGB-3111
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/_R_-Zanubrutinib.html
Purity
98.97
Solubility
DMSO : ≥ 64.25 mg/mL
Smiles
NC(C1=C2N(N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)[C@@H](C5CCN(C(C=C)=O)CC5)CCN2)=O
Molecular Formula
C27H29N5O3
Molecular Weight
471.55
References & Citations
[1]Wu J, et al. Acalabrutinib (ACP-196) : a selective second-generation BTK inhibitor. J Hematol Oncol. 2016 Mar 9;9:21.|[2]Wu J, et al. Second-generation inhibitors of Bruton tyrosine kinase. J Hematol Oncol. 2016 Sep 2;9 (1) :80.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940965-100 1x 100 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402424-100 1x 100 µL
BOB.1 (B-Cell Marker) (BOB1/2424), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882561-500 1x 500 µL
NKX6.1 (Marker for Pancreatic and Duodenal Neuroendocrine Tumors) (NKX61/2561), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681203-100 1x 100 µL
Smooth Muscle Actin (ACTA2/791 +1A4), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details