Microcystin-RR
Product Specifications
UNSPSC Description
Microcystin-RR (Cyanoviridin RR) is a potent and orally active protein phosphatase inhibitor. Microcystin-RR induces Apoptosis and ER stress in mice liver[1][2].
Target Antigen
Apoptosis; Phosphatase
Type
Peptides
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
99.40
Solubility
10 mM in DMSO
Smiles
CC(/C=C/[C@@H]([C@@H](C(N[C@H](CCC(N(C(C(N[C@@H]1C)=O)=C)C)=O)C(O)=O)=O)C)NC([C@@H](NC([C@H]([C@@H](NC([C@](NC1=O)([H])CCCNC(N)=N)=O)C(O)=O)C)=O)CCCNC(N)=N)=O)=C\[C@H](C)[C@@H](OC)CC2=CC=CC=C2
Molecular Weight
1038.20
References & Citations
[1]Matsushima R, et al. In vitro and in vivo effects of protein phosphatase inhibitors, microcystins and nodularin, on mouse skin and fibroblasts. Biochem Biophys Res Commun. 1990 Sep 14;171(2):867-74.|[2]Huang P, et al. The apoptotic effect of oral administration of microcystin-RR on mice liver. Environ Toxicol. 2011 Oct;26(5):443-52.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Clinical Information
No Development Reported
CAS Number
111755-37-4
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