Gp100 (25-33), human (TFA)

Gp100 (25-33), human TFA (Hgp100 (25-33) (TFA) ) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human TFA is a 9-amino acid (AA) epitope restricted by MHC class I H-2Db and recognized by the T cells. Gp100 (25-33), human TFA has immunogenicity and induces specific T cells. Gp100 (25-33), human TFA can be used for the cancer research, such as melanoma[1].

Product Specifications

Product Name Alternative

Hgp100 (25-33) (TFA)

UNSPSC

12352209

Target

MHC

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gp100-25-33-human-tfa.html

Purity

99.73

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N.OC(C(F)(F)F)=O

Molecular Formula

C54H83F3N16O16

Molecular Weight

1269.33

References & Citations

[1]Overwijk WW, et al. gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand. J Exp Med. 1998 Jul 20;188 (2) :277-86.