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8-iso Prostaglandin F1β

Selected Variant

HY-130448-01

Size: 1 mg

8-iso Prostaglandin F1β is an isoprostane, that exhibits vasoconstrictive effect in neonatal porcine pulmonary arteries, pulmonary veins, and mesenteric arteries. 8-iso Prostaglandin F1β targets TXA2 receptor and exhibits the blood vessel contractile efficacy under the influence of tyrosine kinase and Rho kinase[1].

Product Specifications

CAS Number

26771-95-9

UNSPSC

12352211

Target

Prostaglandin Receptor; ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; GPCR/G Protein; Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/8-iso-prostaglandin-f1β.html

Smiles

CCCCC[C@H](O)/C=C/[C@@H]1[C@@H]([C@H](O)C[C@H]1O)CCCCCCC(O)=O

Molecular Formula

C20H36O5

Molecular Weight

356.50

References & Citations

[1]González-Luis G, et al., Age-related differences in vasoconstrictor responses to isoprostanes in piglet pulmonary and mesenteric vascular smooth muscle. Pediatr Res. 2005 Jun;57 (6) :845-52.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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