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Phosphatidylinositol-1,2-dioctanoyl (sodium)

Selected Variant

HY-W854295

Size: 100 µg

Phosphatidylinositol-1,2-dioctanoyl sodium significantly inhibits transmembrane P-gp transport in a reproducible, cell line-independent, and substrate-independent manner. Phosphatidylinositol-1,2-dioctanoyl sodium plays an important role in signal transduction and cell movement[1].

Product Specifications

CAS Number

899827-36-2

Product Name Alternative

PtdIns- (1,2-dioctanoyl) (sodium)

UNSPSC

12352211

Target

P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/phosphatidylinositol-1-2-dioctanoyl-sodium.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCC(OC[C@@H](OC(CCCCCCC)=O)COP(O[C@H]1[C@@H]([C@H]([C@@H]([C@H]([C@H]1O)O)O)O)O)(O[Na])=O)=O

Molecular Formula

C25H46NaO13P

Molecular Weight

608.59

References & Citations

[1]Lucas X, et al. Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies. PLoS One. 2013 Apr 9;8 (4) :e60679. |[2]Lucas X, et al. Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies. PLoS One. 2013 Apr 9;8 (4) :e60679.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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