Lucidenic lactone
Product Specifications
UNSPSC Description
Lucidenic lactone is a terpene compound, is a DNA polymerase inhibitor. Lucidenic lactone inhibits calf DNA polymerase-α, rat DNA polymerase-β, and HIV-1 reverse transcriptase with IC50 values of 42 μM, 99 μM, and 69 μM, respectively[1].
Target Antigen
DNA/RNA Synthesis; HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lucidenic-lactone.html
Smiles
C[C@@]12[C@](C3=C([C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])C[C@@H]3O)C)C(C1)=O)([C@H](C[C@@H]2C5(CCC(O5)=O)CO)O)C
Molecular Weight
476.60
References & Citations
[1]Mizushina Y, et al. Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Bioorg Med Chem. 1999 Sep;7(9):2047-52.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N13712/Lucidenic-lactone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N13712/
Clinical Information
No Development Reported
CAS Number
250643-34-6
Curated Selection
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