Lucidenic lactone
Lucidenic lactone is a terpene compound, is a DNA polymerase inhibitor. Lucidenic lactone inhibits calf DNA polymerase-α, rat DNA polymerase-β, and HIV-1 reverse transcriptase with IC50 values of 42 μM, 99 μM, and 69 μM, respectively[1].
Product Specifications
CAS Number
250643-34-6
UNSPSC
12352211
Target
DNA/RNA Synthesis; HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lucidenic-lactone.html
Smiles
C[C@@]12[C@](C3=C([C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])C[C@@H]3O)C)C(C1)=O)([C@H](C[C@@H]2C5(CCC(O5)=O)CO)O)C
Molecular Formula
C27H40O7
Molecular Weight
476.60
References & Citations
[1]Mizushina Y, et al. Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Bioorg Med Chem. 1999 Sep;7 (9) :2047-52.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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