CD25/Interleukin-2Rα Chimeric Monoclonal Antibody (aa 116-122)

<strong>CD25/Interleukin-2Rα Chimeric Monoclonal Antibody (aa 116-122)</strong>_x000D_ <strong>Catalog number:</strong> B2017691_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> p55, Cluster of Differentiation 25, Interleukin-2 Receptor Subunit α, ILR2α, Tac_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bernett MJ, Karki S, Moore GL, Leung IW, Chen H, Pong E, Nguyen DH, Jacinto J, Zalevsky J, Muchhal US, Desjarlais JR, Lazar GA. Engineering fully human monoclonal antibodies from murine variable regions J Mol Biol. 2010 Mar 12;396(5):1474-90._x000D_ 2: Okawaki M, Yamaguchi Y, Okita R, Ohara M, Okada M. Dose-finding study of anti-CD25 antibody for targeting regulatory T cells in locoregional immunotherapy of malignant effusion Hiroshima J Med Sci. 2008 Mar;57(1):37-46._x000D_ 3: Kwekkeboom J, Warlé MC, Rietveld J, Segeren KC, Tilanus HW, Metselaar HJ. Blockade of intragraft IL-2 receptor-alpha by basiliximab is insufficient to prevent activation of liver graft infiltrating cells Transpl Immunol. 2003 Jan-Mar;11(1):1-5._x000D_ 4: Vincenti F. Potential of daclizumab in solid organ transplantation BioDrugs. 1999 May;11(5):333-41._x000D_ 5: Fujimura K, Oyamada A, Iwamoto Y, Yoshikai Y, Yamada H. CD4 T cell-intrinsic IL-2 signaling differentially affects Th1 and Th17 development J Leukoc Biol. 2013 Aug;94(2):271-9._x000D_ 6: Charles KA, Kulbe H, Soper R, Escorcio-Correia M, Lawrence T, Schultheis A, Chakravarty P, Thompson RG, Kollias G, Smyth JF, Balkwill FR, Hagemann T. The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans J Clin Invest. 2009 Oct;119(10):3011-23._x000D_ 7: Rudolph M, Hebel K, Miyamura Y, Maverakis E, Brunner-Weinzierl MC. Blockade of CTLA-4 decreases the generation of multifunctional memory CD4+ T cells in vivo J Immunol. 2011 May 15;186(10):5580-9._x000D_ 8: Imeri J, Marcoux P, Huyghe M, Desterke C, Fantacini DMC, Griscelli F, Covas DT, de Souza LEB, Griscelli AB, Turhan AG. Chimeric antigen-receptor (CAR) engineered natural killer cells in a chronic myeloid leukemia (CML) blast crisis model Front Immunol. 2024 Jan 8;14:1309010._x000D_ 9: Liu G, Duan K, Ma H, Niu Z, Peng J, Zhao Y. An instructive role of donor macrophages in mixed chimeras in the induction of recipient CD4(+)Foxp3(+) Treg cells Immunol Cell Biol. 2011 Nov;89(8):827-35._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/16129059">10: Liu LH, Sun QY, Hu KX, Fan CB, Huang YJ, Bian L, Xiao XB, Yao B, Guo M, Yu CL, Ai HS. [Establishment of rhesus model for haploidentical hematopoietic stem cell transplantation with nonmyeloablative conditioning] Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2005 Aug;13(4):677-82.</a>_x000D_ _x000D_ <strong>Products Related to CD25/Interleukin-2Rα Chimeric Monoclonal Antibody (aa 116-122) can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>