3-Phenoxybenzoic acid-13C6

3-Phenoxybenzoic acid-13C6 is the 13C6 labeled 3-Phenoxybenzoic acid. 3-Phenoxybenzoic acid is the metabolite of pyrethroid insecticides. 3-Phenoxybenzoic acid induces immunotoxicity and oxidative stress, and inhibits the phagocytic ability of macrophages[1].

Product Specifications

CAS Number

[1793055-05-6]

Product Name Alternative

3-PBA-13C6

UNSPSC

12352005

Target

Apoptosis; Drug Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-phenoxybenzoic-acid-13c6.html

Purity

99.29

Solubility

10 mM in DMSO

Smiles

OC(C1=CC=CC(O[13C]2=[13CH][13CH]=[13CH][13CH]=[13CH]2)=C1)=O

Molecular Formula

C7 13C6H10O3

Molecular Weight

220.17

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Wang X, et al., β-Cypermethrin and its metabolite 3-phenoxybenzoic acid exhibit immunotoxicity in murine macrophages. Acta Biochim Biophys Sin (Shanghai) . 2017 Dec 1;49 (12) :1083-1091.