Influenza A [Wisconsin/67/2022 (H1N1) ] Neuraminidase (NA) Protein, His Tag

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 56.4 kDa. The protein migrates as 55 kDa, 65 kDa and 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Immobilized Influenza A [Wisconsin/67/2022(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524m) at 1 μg/mL (100 μL/well) can bind  Anti- NA(A/PAN) ,Mouse IgG with a linear range of 0.1-4 ng/mL (QC tested).