Insulin-like Growth Factor-1 (Human)

<strong>Insulin-like Growth Factor-1 (Human)</strong>_x000D_ <strong>Catalog number:</strong> B2010278_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Insulin-like Growth Factor-1 (Human) expressed in E. coli. This protein acts as a mitogenic cytokine that binds to IGF type 1 receptor. This protein modulates cell growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle and more._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Nicholls AR, Holt RI. Growth Hormone and Insulin-Like Growth Factor-1. Front_x000D_ Horm Res. 2016;47:101-14._x000D_ _x000D_ 2: Rothe MJ, Altman RD, Falanga V. Plasma somatomedin-C levels in systemic_x000D_ sclerosis. Br J Dermatol. 1988 Nov;119(5):639-42._x000D_ _x000D_ 3: Saito Y, Ishii Y, Niwa M, Ueda I. Direct expression of a synthetic_x000D_ somatomedin C gene in Escherichia coli by use of a two-cistron system. J_x000D_ Biochem. 1987 May;101(5):1281-8._x000D_ _x000D_ 4: Chatelain P, Perrard-Sapori MH, Jaillard C, Naville D, Ruitton A, Saez J._x000D_ Somatomedin-C/insulin-like growth factor 1: a differentiating factor of_x000D_ testicular function. Int J Rad Appl Instrum B. 1987;14(6):617-22._x000D_ _x000D_ 5: Trippel SB, Corvol MT, Dumontier MF, Rappaport R, Hung HH, Mankin HJ. Effect_x000D_ of somatomedin-C/insulin-like growth factor I and growth hormone on cultured_x000D_ growth plate and articular chondrocytes. Pediatr Res. 1989 Jan;25(1):76-82._x000D_ _x000D_ 6: Bennett RM, Clark SR, Campbell SM, Burckhardt CS. Low levels of somatomedin C_x000D_ in patients with the fibromyalgia syndrome. A possible link between sleep and_x000D_ muscle pain. Arthritis Rheum. 1992 Oct;35(10):1113-6._x000D_ _x000D_ 7: Nishijima M. Somatomedin-C as a fetal growth promoting factor and amino acid_x000D_ composition of cord blood in Japanese neonates. J Perinat Med. 1986;14(3):163-9._x000D_ _x000D_ 8: Nickoloff BJ, Misra P, Morhenn VB, Hintz RL, Rosenfeld RG. Further_x000D_ characterization of the keratinocyte somatomedin-C/insulin-like growth factor I_x000D_ (SM-C/IGF-I) receptor and the biological responsiveness of cultured_x000D_ keratinocytes to SM-C/IGF-I. Dermatologica. 1988;177(5):265-73._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/3067520/">9: Hansson HA, Engström AM, Holm S, Rosenqvist AL. Somatomedin C_x000D_ immunoreactivity in the Achilles tendon varies in a dynamic manner with the_x000D_ mechanical load. Acta Physiol Scand. 1988 Oct;134(2):199-208. </a>_x000D_ _x000D_ <strong>Products Related to Insulin-like Growth Factor-1 (Human) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>