Influenza A [A/Darwin/9/2021 (H3N2) ] Neuraminidase (NA) Protein, His Tag (MALS & SPR verified)

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 51 kDa. The protein migrates as 70-90 kDa and 170 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.