Cathepsin K Substrate (Highly Pure)

<strong>Cathepsin K Substrate (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2011259_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 0.1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 919 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> CatK substrate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Law S, Du X, Panwar P, Honson NS, Pfeifer T, Roberge M, Brömme D. Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening Biochem J. 2019 Feb 5;476(3):499-512._x000D_ 2: Lecaille F, Weidauer E, Juliano MA, Brömme D, Lalmanach G. Probing cathepsin K activity with a selective substrate spanning its active site Biochem J. 2003 Oct 15;375(Pt 2):307-12._x000D_ 3: Tada S, Tsutsumi K, Ishihara H, Suzuki K, Gohda K, Teno N. Species differences between human and rat in the substrate specificity of cathepsin K J Biochem. 2008 Oct;144(4):499-506._x000D_ 4: Aibe K, Yazawa H, Abe K, Teramura K, Kumegawa M, Kawashima H, Honda K. Substrate specificity of recombinant osteoclast-specific cathepsin K from rabbits Biol Pharm Bull. 1996 Aug;19(8):1026-31._x000D_ 5: Lecaille F, Brömme D, Lalmanach G. Biochemical properties and regulation of cathepsin K activity Biochimie. 2008 Feb;90(2):208-26._x000D_ 6: Lecaille F, Chazeirat T, Bojarski KK, Renault J, Saidi A, Prasad VGNV, Samsonov S, Lalmanach G. Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity Biochim Biophys Acta Proteins Proteom. 2020 Feb;1868(2):140318._x000D_ 7: Camardo A, Carney S, Ramamurthi A. Assessing the targeting and fate of cathepsin k antibody-modified nanoparticles in a rat abdominal aortic aneurysm model Acta Biomater. 2020 Aug;112:225-233._x000D_ 8: Zhang D, Leung N, Weber E, Saftig P, Brömme D. The effect of cathepsin K deficiency on airway development and TGF-β1 degradation Respir Res. 2011 May 31;12(1):72._x000D_ 9: Barry ZT, Platt MO. Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation J Biol Chem. 2012 Aug 10;287(33):27723-30._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23430258">10: Fields GB. Interstitial collagen catabolism J Biol Chem. 2013 Mar 29;288(13):8785-93. </a>_x000D_ _x000D_ <strong>Products Related to Cathepsin K Substrate (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>