TAT-P4- (DATC5) 2 (TFA)
TAT-P4- (DATC5) 2 TFA is a high-affinity peptide inhibitor of the PICK1 (protein interacting with C kinase-1) PDZ domain, with a Ki of 1.7 nM. TAT-P4- (DATC5) 2 TFA can inhibit addiction in rats[1].
Product Specifications
UNSPSC
12352209
Target
PKC
Type
Peptides
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tat-p4-datc5-2-tfa.html
Solubility
10 mM in DMSO
Smiles
[HWLKV]C(CCOCCOCC[N-RRRQRRKKRGY]CCOCCOCCC([HWLKV])=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C152H247F3N52O34
Molecular Weight
3403.97
References & Citations
[1]Christopher Turner, et al. Administration of a Novel High Affinity PICK1 PDZ Domain Inhibitor Attenuates Cocaine Seeking in Rats. Neuropharmacology. 2020 Mar 1;164:107901.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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