Castanospermine (Highly Pure)

<strong>Castanospermine (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2012508_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 189.2 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 6,7-Diepicastanospermine, 6-Epicastanospermine, 1,6,7,8-Tetrahydroxyoctahydroindolizine_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Noda N, Ozawa T. Castanospermine suppresses CD44 ectodomain cleavage as revealed by transmembrane bioluminescent sensors J Cell Sci. 2022 Mar 15;135(6):jcs259314._x000D_ 2: Clarke EC, Nofchissey RA, Ye C, Bradfute SB. The iminosugars celgosivir, castanospermine and UV-4 inhibit SARS-CoV-2 replication Glycobiology. 2021 May 3;31(4):378-384._x000D_ 3: Myeong IS, Lee YT, Kang J, Ham WH. Stereoselective Total Syntheses of (+)-Castanospermine and Neu5Ac Methyl Ester J Org Chem. 2019 Apr 5;84(7):4211-4220._x000D_ 4: Hibberd AD, Clark DA, Trevillian PR, Mcelduff P. Interaction between castanospermine an immunosuppressant and cyclosporin A in rat cardiac transplantation World J Transplant. 2016 Mar 24;6(1):206-14._x000D_ 5: Tharappel AM, Cheng Y, Holmes EH, Ostrander GK, Tang H. Castanospermine_ reduces Zika virus infection-associated seizure by inhibiting both the viral load and inflammation in mouse models Antiviral Res. 2020 Nov;183:104935._x000D_ 6: Yun H, Kim J, Sim J, Lee S, Han YT, Chang DJ, Kim DD, Suh YG. Asymmetric syntheses of 1-deoxy-6,8a-di-epi-castanospermine and 1-deoxy-6-epi-castanospermine J Org Chem. 2012 Jun 15;77(12):5389-93._x000D_ 7: Saul R, Chambers JP, Molyneux RJ, Elbein AD. Castanospermine_, a tetrahydroxylated alkaloid that inhibits beta-glucosidase and beta-glucocerebrosidase Arch Biochem Biophys. 1983 Mar;221(2):593-7._x000D_ 8: Whitby K, Pierson TC, Geiss B, Lane K, Engle M, Zhou Y, Doms RW, Diamond MS. Castanospermine_, a potent inhibitor of dengue virus infection in vitro and in vivo J Virol. 2005 Jul;79(14):8698-706._x000D_ 9: Pan YT, Hori H, Saul R, Sanford BA, Molyneux RJ, Elbein AD. Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin Biochemistry. 1983 Aug 2;22(16):3975-84._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/24124558">10: Allan G, Ouadid-Ahidouch H, Sanchez-Fernandez EM, Risquez-Cuadro R, Fernandez JM, Ortiz-Mellet C, Ahidouch A. New castanospermine glycoside analogues inhibit breast cancer cell proliferation and induce apoptosis without affecting normal cells PLoS One. 2013 Oct 4;8(10):e76411. </a>_x000D_ _x000D_ <strong>Products Related to Castanospermine (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>