Vismodegib-d4
Vismodegib-d4 is deuterium labeled Vismodegib. Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2].
Product Specifications
CAS Number
1450990-33-6
UNSPSC
12352005
Target
Autophagy; Hedgehog; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
ClC1=CC=C(C=C1C2=C([2H])C([2H])=C([2H])C([2H])=N2)NC(C3=C(Cl)C=C(S(C)(=O)=O)C=C3)=O
Molecular Formula
C19H10D4Cl2N2O3S
Molecular Weight
425.32
References & Citations
2+
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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