BTT-266
BTT-266 is an antagonist forcalcium channel, through suppression of the CaVα1-AID-CaVβ3 interaction, with a Ki of 1.4 μM. BTT-266 modulates the activation of voltage-dependent CaV2.2. BTT-266 exhibits analgesic efficacy against neuropathic pain in rats model[1].
Product Specifications
CAS Number
[2413939-89-4]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/btt-266.html
Purity
98.90
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC(C(N2N=C(CC2C3=CN(C4=CC=CC=C4)N=C3C5=CC=C(C)C=C5)C6=CC=C(OC)C=C6)=O)=C1)O
Molecular Formula
C34H28N4O4
Molecular Weight
556.61
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115597/BTT-266-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115597/BTT-266-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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