Human CD151 Protein, Flag, His Tag (Detergent)

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

Product Specifications

Background

Specifications

This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.2 kDa.

Accession Number

P48509

Expression Region

Gly 2 - Tyr 253

Host

HEK293

Target

CD151

Conjugation

Unconjugated

Tag

N-Flag & C-10xHis

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Bioactivity

Immobilized Human CD151 Protein, Flag,His Tag (Cat. No. CD1-H52D3) at 1 μg/mL (100 μL/well) can bind Anti-CD151 Antibody with a linear range of 0.1-4 ng/mL (QC tested).