Recombinant AKT1 Protein

<strong>Recombinant AKT1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017519_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~ 81 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Jo EH, Ahn JS, Mo JS, Yoon JH, Ann EJ, Baek HJ, Lee HJ, Kim SH, Kim MY, Park HS. Akt1 phosphorylates Nicastrin to regulate its protein stability and activity J Neurochem. 2015 Sep;134(5):799-810._x000D_ 2: McGinnis JE, Venegas LA, Lopez H, Kay BK. A Recombinant Affinity Reagent Specific for a Phosphoepitope of Akt1 Int J Mol Sci. 2018 Oct 24;19(11):3305._x000D_ 3: Kim AH, Sasaki T, Chao MV. JNK-interacting protein 1 promotes Akt1 activation J Biol Chem. 2003 Aug 8;278(32):29830-6._x000D_ 4: Yang W, Ju JH, Lee KM, Nam K, Oh S, Shin I. Protein kinase B/Akt1 inhibits autophagy by down-regulating UVRAG expression Exp Cell Res. 2013 Feb 1;319(3):122-33._x000D_ 5: Chin YR, Toker A. The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration Mol Cell. 2010 May 14;38(3):333-44._x000D_ 6: Deng W, Leu HB, Chen Y, Chen YH, Epperson CM, Juang C, Wang PH. Protein kinase B (PKB/AKT1) formed signaling complexes with mitochondrial proteins and prevented glycolytic energy dysfunction in cultured cardiomyocytes during ischemia-reperfusion injury Endocrinology. 2014 May;155(5):1618-28._x000D_ 7: Girardi C, James P, Zanin S, Pinna LA, Ruzzene M. Differential phosphorylation of Akt1 and Akt2 by protein kinase CK2 may account for isoform specific functions Biochim Biophys Acta. 2014 Sep;1843(9):1865-74._x000D_ 8: Yamada T, Katagiri H, Asano T, Inukai K, Tsuru M, Kodama T, Kikuchi M, Oka Y. 3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells J Biol Chem. 2001 Feb 16;276(7):5339-45._x000D_ 9: Kawamura M, Umehara D, Odahara Y, Miyake A, Ngo MH, Ohsato Y, Hisasue M, Nakaya MA, Watanabe S, Nishigaki K. AKT capture by feline leukemia virus Arch Virol. 2017 Apr;162(4):1031-1036._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26579576">10: Basson MD, Zeng B, Wang S. Akt1 binds focal adhesion kinase via the Akt1 kinase domain independently of the pleckstrin homology domain J Physiol Pharmacol. 2015 Oct;66(5):701-9.</a>_x000D_ _x000D_ <strong>Products Related to Recombinant AKT1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>