HSD17B13-IN-97
HSD17B13-IN-97 (compound 4) is a potent hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor with an IC50 value of ≤0.1 µM. HSD17B13-IN-97 has the potential for the research of Nonalcoholic fatty liver diseases (NAFLDs), nonalcoholic steatohepatitis (NASH) or or drug induced liver injury (DILI) [1].
Product Specifications
CAS Number
[2849338-44-7]
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-97.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C(F)(F)F)N=C(C(NC2=CC=CC(N=CN3CC4=CC=CC=C4F)=C2C3=O)=O)C=C1
Molecular Formula
C22H14F4N4O3
Molecular Weight
458.37
References & Citations
[1]Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. WO2022216626A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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