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HSD17B13-IN-97

HSD17B13-IN-97 (compound 4) is a potent hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) inhibitor with an IC50 value of ≤0.1 µM. HSD17B13-IN-97 has the potential for the research of Nonalcoholic fatty liver diseases (NAFLDs), nonalcoholic steatohepatitis (NASH) or or drug induced liver injury (DILI) [1].

Product Specifications

CAS Number

[2849338-44-7]

UNSPSC

12352005

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hsd17b13-in-97.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C(F)(F)F)N=C(C(NC2=CC=CC(N=CN3CC4=CC=CC=C4F)=C2C3=O)=O)C=C1

Molecular Formula

C22H14F4N4O3

Molecular Weight

458.37

References & Citations

[1]Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. WO2022216626A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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