2'-O-MB-cGMP (sodium)
2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium is a cyclic GMP-specific phosphodiesterase inhibitor with an I50 value of 35 µM. 2'-O-MB-cGMP (2′-O-Monobutyryl-cGMP) sodium inhibits Ca2+ dependent phosphodiesterase hydrolysis using cAMP or cGMP as substrate[1].
Product Specifications
CAS Number
58329-72-9
Product Name Alternative
2′-O-Monobutyryl-cGMP (sodium)
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-o-mb-cgmp-sodium.html
Smiles
O=C(NC(N)=N1)C2=C1N(C=N2)[C@@H]3O[C@H](CO4)[C@@H](OP4(O[Na])=O)[C@H]3OC(CCC)=O
Molecular Formula
C14H17N5NaO8P
Molecular Weight
437.28
References & Citations
[1]Davis CW. Selective alteration of Ca2+-dependent and Ca2+-independent cyclic nucleotide phosphodiesterase activity in rat cerebral cortex by cyclic nucleotides and their analogs. Biochim Biophys Acta. 1982 Jul 12;705 (1) :1-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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