STING-IN-9
STING-IN-9 (compound 2) is a potent inhibitor of human CYP11B2. STING-IN-9 showed more than 80 times higher selectivity over human CYP11B1 in vitro[1].
Product Specifications
UNSPSC
12352005
Target
Mineralocorticoid Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sting-in-9.html
Smiles
N#CC1=CC=C(NC2=NC=NC=C2S(C(C)(C)CCCS(C)(=O)=O)(=O)=O)C=C1
Molecular Formula
C18H22N4O4S2
Molecular Weight
422.52
References & Citations
[1]Masaki Meguro, et al. Identification of sulfonylpyrimidines as novel selective aldosterone synthase (CYP11B2) inhibitors. Bioorg Med Chem. 2024 Jun 15:108:117775.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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