3′-O-Methyladenosine
(2R,3R,4S,5R) -2- (6-amino-9H-purin-9-yl) -5- (hydroxymethyl) -4-methoxytetrahydrofuran-3-ol (Adenosine, 3'-O-methyl- (8CI) (9CI) ) is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].
Product Specifications
CAS Number
[10300-22-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/3-o-methyladenosine.html
Concentration
10mM
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](OC)[C@@H](CO)O[C@H]1N2C=NC3=C(N=CN=C32)N
Molecular Formula
C11H15N5O4
Molecular Weight
281.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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