Recombinant JAK1 (438-1154) Protein

<strong>Recombinant JAK1 (438-1154) Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017653_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 83.6 kDa_x000D_ <strong>Supplied as:</strong> SOLUTION_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Janus Kinase 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Nault JC, Couchy G, Balabaud C, Morcrette G, Caruso S, Blanc JF, Bacq Y, Calderaro J, Paradis V, Ramos J, Scoazec JY, Gnemmi V, Sturm N, Guettier C, Fabre M, Savier E, Chiche L, Labrune P, Selves J, Wendum D, Pilati C, Laurent A, De Muret A, Le Bail B, Rebouissou S, Imbeaud S; GENTHEP Investigators; Bioulac-Sage P, Letouzé E, Zucman-Rossi J. Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation Gastroenterology. 2017 Mar;152(4):880-894.e6._x000D_ 2: Reshmi SC, Harvey RC, Roberts KG, Stonerock E, Smith A, Jenkins H, Chen IM, Valentine M, Liu Y, Li Y, Shao Y, Easton J, Payne-Turner D, Gu Z, Tran TH, Nguyen JV, Devidas M, Dai Y, Heerema NA, Carroll AJ 3rd, Raetz EA, Borowitz MJ, Wood BL, Angiolillo AL, Burke MJ, Salzer WL, Zweidler-McKay PA, Rabin KR, Carroll WL, Zhang J, Loh ML, Mullighan CG, Willman CL, Gastier-Foster JM, Hunger SP. Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group Blood. 2017 Jun 22;129(25):3352-3361._x000D_ 3: Bose P, Verstovsek S. Developmental Therapeutics in Myeloproliferative Neoplasms Clin Lymphoma Myeloma Leuk. 2017 Jul;17S:S43-S52._x000D_ 4: Dey P, Li J, Zhang J, Chaurasiya S, Strom A, Wang H, Liao WT, Cavallaro F, Denz P, Bernard V, Yen EY, Genovese G, Gulhati P, Liu J, Chakravarti D, Deng P, Zhang T, Carbone F, Chang Q, Ying H, Shang X, Spring DJ, Ghosh B, Putluri N, Maitra A, Wang YA, DePinho RA. Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment Cancer Discov. 2020 Apr;10(4):608-625._x000D_ 5: Tovey MG, Lallemand C. Safety, Tolerability, and Immunogenicity of Interferons Pharmaceuticals (Basel). 2010 Apr 20;3(4):1162-1186._x000D_ 6: Zhao L, Li J, Mo G, Cao D, Li C, Huang G, Jiang L, Chen G, Yao H, Peng X. Recombinant protein EBI3 attenuates Clonorchis sinensis-induced liver fibrosis by inhibiting hepatic stellate cell activation in mice Parasit Vectors. 2023 Jul 21;16(1):246._x000D_ 7: Wei YF, Li X, Zhao MR, Liu S, Min L, Zhu ST, Zhang ST, Xie SA. Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3 Cell Commun Signal. 2024 May 10;22(1):263._x000D_ 8: Huang L, Chen W, Liu H, Xue M, Dong S, Liu X, Feng C, Cao S, Ye G, Zhou Q, Zhang Z, Zheng J, Li J, Zhao D, Wang Z, Sun E, Chen H, Zhang S, Wang X, Zhang X, He X, Guan Y, Bu Z, Weng C. African Swine Fever Virus HLJ/18 CD2v Suppresses Type I IFN Production and IFN-Stimulated Genes Expression through Negatively Regulating cGMP-AMP Synthase-STING and IFN Signaling Pathways J Immunol. 2023 May 1;210(9):1338-1350._x000D_ 9: Vainchenker W, Dusa A, Constantinescu SN. JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies Semin Cell Dev Biol. 2008 Aug;19(4):385-93._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8331382">10: Yang X, Chung D, Cepko CL. Molecular cloning of the murine JAK1 protein tyrosine kinase and its expression in the mouse central nervous system J Neurosci. 1993 Jul;13(7):3006-17. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant JAK1 (438-1154) Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>