OX1a
OX1a (OLC20) is an Orco antagonist with non-competitive activity that inhibits the activation of oxygen odor receptors (ORs) . OX1a is able to reduce the activation of ORs by competitively inhibiting the effects of Orco agonists. OX1a also shows non-competitive inhibition of odor molecules, which may affect the olfactory-mediated behavior of insects. Through structural optimization, OX1a analogs have shown higher antagonistic potency, indicating that this type of compound may have application potential in a wide range of insect species[1].
Product Specifications
CAS Number
[136340-88-0]
Product Name Alternative
OLC20
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Olfactory Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ox1a.html
Smiles
O=C(NC1=CC=C(C=C1)CC)C2=CC=CS2
Molecular Formula
C13H13NOS
Molecular Weight
231.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Phenylthiophenecarboxamide antagonists of the olfactory receptor co-receptor subunit from a mosquito
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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